In addition to lixoftConnectors, an R package called Rsmlx provides powerful tools for automatic PK model building and likelihood profiling for computing confidence intervals. The Rsmlx package uses and depends on the MonolixSuite software and the lixoftConnectors R package.
This page gives an overview of the Rsmlx package functions.
Installation instructions
Model building
- buildmlx – automatic statistical model building (covariate model, correlation model, error model)
- buildVar – automatic variability model building
- buildAll – complete automatic statistical model building
- pkbuild – automatic PK model building
Model evaluation
- confintmlx – compute confidence intervals for the population parameters estimated by Monolix
