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In addition to lixoftConnectors, an R package called Rsmlx provides powerful tools for automatic PK model building, bootstrap simulation and likelihood profiling for
computing confidence intervals. Rsmlx package uses and depends on lixoftConnectors.

This is a page that links to pages describing the Rsmlx package functions.

Installation instructions

Model building

  • buildmlx – automatic statistical model building (covariate model, correlation model, error model)
  • buildVar – automatic variability model building
  • buildAll – complete automatic statistical model building
  • pkbuild – automatic PK model building

Model evaluation

  • confintmlx – compute confidence intervals for the population parameters estimated by Monolix
  • bootmlx – bootstrapping – case resampling